BRMS-1 rabbit pAb
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
BRMS1; Breast cancer metastasis-suppressor 1
Gene ID
25855
UniProt
Q9HCU9
Cellular Locus
Nucleus. Cytoplasm. Predominantly nuclear.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human BRMS1. AA range:197-246
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
28kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3888-1.pdf
Observed Molecular Weight
28 kD
Subcellular Location
Nucleus. Cytoplasm. Predominantly nuclear.
Other Product Names
BRMS1; Breast cancer metastasis-suppressor 1
Gene ID (Human)
25855
SwissProt (Human)
Q9HCU9
Available Sizes
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