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Sg III rabbit pAb

Secretogranin III (SCG3) Homo sapiens The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

Product Specifications

Background

Secretogranin III (SCG3) Homo sapiens The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Synonyms

SCG3; Secretogranin-3; Secretogranin III; SgIII

Gene ID

29106

UniProt

Q8WXD2

Cellular Locus

Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane ; Peripheral membrane protein. Secreted. Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts..

Host

Rabbit

Species Reactivity

Human,Rat

Reactivity

Human; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from the N-terminal region of human SCG3. AA range:21-70

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

53kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3872-1.pdf

Observed Molecular Weight

53 kD

Subcellular Location

Cytoplasmic vesicle, secretory vesicle . Cytoplasmic vesicle, secretory vesicle membrane ; Peripheral membrane protein . Secreted . Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts. .

Other Product Names

SCG3; Secretogranin-3; Secretogranin III; SgIII

Gene ID (Human)

29106

SwissProt (Human)

Q8WXD2

Available Sizes

Curated Selection

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