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TRP14 rabbit pAb

Function: Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide. PTM: The oxidized protein is reduced by TRXR1. similarity: Belongs to the thioredoxin family. similarity: Contains 1 thioredoxin domain. subunit: Interacts with TRXR1 and DYNLL1/DNCL1. tissue specificity: Ubiquitously expressed in cell lines.

Product Specifications

Background

Function:Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide., PTM:The oxidized protein is reduced by TRXR1., similarity:Belongs to the thioredoxin family., similarity:Contains 1 thioredoxin domain., subunit:Interacts with TRXR1 and DYNLL1/DNCL1., tissue specificity:Ubiquitously expressed in cell lines.

Synonyms

TXNDC17; TXNL5; Thioredoxin domain-containing protein 17; 14 kDa thioredoxin-related protein; TRP14; Protein 42-9-9; Thioredoxin-like protein 5

Gene ID

84817

UniProt

Q9BRA2

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from TRP14 . at AA range: 20-100

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

13kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3861-1.pdf

Observed Molecular Weight

13 kD

Subcellular Location

Cytoplasm .

Other Product Names

TXNDC17; TXNL5; Thioredoxin domain-containing protein 17; 14 kDa thioredoxin-related protein; TRP14; Protein 42-9-9; Thioredoxin-like protein 5

Gene ID (Human)

84817

SwissProt (Human)

Q9BRA2

Available Sizes

Curated Selection

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