Chymase rabbit pAb
Chymase 1 (CMA1) Homo sapiens This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015],
Product Specifications
Background
Product Name Alternative
CMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I
UniProt
P23946
Swiss Prot
P23946
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from the Internal region of human Chymase.
Target
Chymase
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
27kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
27kD
Fragment
IgG
Subcellular Location
Secreted. Cytoplasmic granule. Mast cell granules.
Other Product Names
CMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I
Gene ID (Human)
1215
Available Sizes
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