Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

27-Hydroxycholesterol

27-Hydroxycholesterol (27-OHC) is a selective estrogen receptor modulator and an agonist of the liver X receptor.

Product Specifications

CAS Number

20380-11-4

Product Name Alternative

27-OHC

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Estrogen Receptor/ERR; LXR

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/27-Hydroxycholesterol.html

Concentration

10mM

Purity

99.77

Solubility

DMSO : 1 mg/mL (ultrasonic) |Ethanol : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@H](CO)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Molecular Formula

C27H46O2

Molecular Weight

402.65

Precautions

H302, H315, H319, H335

References & Citations

[1]DuSell CD, et al. 27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. Mol Endocrinol. 2008 Jan;22 (1) :65-77.|[2]Raza S, et al. The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells. Cancer Cell Int. 2017 May 11;17:52.|[3]Kimbung S, et al. Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer. Endocr Relat Cancer. 2017 Jul;24 (7) :339-349.|[4]Fu X, et al. 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. J Biol Chem. 2001 Oct 19;276 (42) :38378-87.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-human Fc mAb
A03B01 1 Each

Anti-human Fc mAb

Sign In for Pricing
View Details
NSE (Enolase, Neuron Specific, ENO2, Enolase 2, Gamma Enolase, 2-phospho-D-glycerate hydro-lyase, Neural enolase)
314843 100 µL

NSE (Enolase, Neuron Specific, ENO2, Enolase 2, Gamma Enolase, 2-phospho-D-glycerate hydro-lyase, Neural enolase)

Sign In for Pricing
View Details
Rabbit Anti-Porcine E-Selectin (SELE) Polyclonal Antibody-[HRP]
VD11N620 1 Each

Rabbit Anti-Porcine E-Selectin (SELE) Polyclonal Antibody-[HRP]

Sign In for Pricing
View Details
Lentiviral mouse Sorbs3 shRNA (UAS) - Lentiviral mouse Sorbs3 shRNA (UAS, RFP) plasmid
GTR15240013 1 Vial

Lentiviral mouse Sorbs3 shRNA (UAS) - Lentiviral mouse Sorbs3 shRNA (UAS, RFP) plasmid

Sign In for Pricing
View Details
MASTERBLOCK®, 96w, U, 1ml/w, polypropylene, subpacked per 5 pieces, CapMat: 381070, 50 pieces per CAR
780215 50 pieces per CAR

MASTERBLOCK®, 96w, U, 1ml/w, polypropylene, subpacked per 5 pieces, CapMat: 381070, 50 pieces per CAR

Sign In for Pricing
View Details
C5orf30 Recombinant Protein (Human)
RP004915 100 µg

C5orf30 Recombinant Protein (Human)

Sign In for Pricing
View Details