Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

27-Hydroxycholesterol

27-Hydroxycholesterol (27-OHC) is a selective estrogen receptor modulator and an agonist of the liver X receptor.

Product Specifications

Product Name Alternative

27-OHC

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Estrogen Receptor/ERR; LXR

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/27-Hydroxycholesterol.html

Concentration

10mM

Purity

99.77

Solubility

DMSO : 1 mg/mL (ultrasonic) |Ethanol : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@H](CO)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Molecular Formula

C27H46O2

Molecular Weight

402.65

Precautions

H302, H315, H319, H335

References & Citations

[1]DuSell CD, et al. 27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. Mol Endocrinol. 2008 Jan;22 (1) :65-77.|[2]Raza S, et al. The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells. Cancer Cell Int. 2017 May 11;17:52.|[3]Kimbung S, et al. Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer. Endocr Relat Cancer. 2017 Jul;24 (7) :339-349.|[4]Fu X, et al. 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. J Biol Chem. 2001 Oct 19;276 (42) :38378-87.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N2371/27-Hydroxycholesterol-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N2371/27-Hydroxycholesterol-SDS-MedChemExpress.pdf

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

CAS Number

[20380-11-4]

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

PGEX-4T-1-PRKDC (2801-3500aa)
PPL01000-1a 1 Each

PGEX-4T-1-PRKDC (2801-3500aa)

Ask
View Details
Yersinia Selective Broth Base
GTR09880360 500 g

Yersinia Selective Broth Base

Ask
View Details
Anti-GFI1 Antibody (Carrier-free Conjugate)
A00888-1-carrier-free 100 µg/Vial

Anti-GFI1 Antibody (Carrier-free Conjugate)

Ask
View Details
Rat α-Glucosidase (α-GUS) Elisa Kit
EK720426 96 Well

Rat α-Glucosidase (α-GUS) Elisa Kit

Ask
View Details
Dcaf12l2 ORF Vector (Mouse) (pORF)
17700014 1.0 µg DNA

Dcaf12l2 ORF Vector (Mouse) (pORF)

Ask
View Details