Actin-α cardiac muscle rabbit pAb
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
ACTC1; ACTC; Actin, alpha cardiac muscle 1; Alpha-cardiac actin
UniProt
P68032
Swiss Prot
P68032
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from Actin-α cardiac muscle . at AA range: 1-80
Target
Actin-α cardiac muscle
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
42kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
42kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton.
Other Product Names
ACTC1; ACTC; Actin, alpha cardiac muscle 1; Alpha-cardiac actin
Gene ID (Human)
70
Available Sizes
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