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RASSF8 rabbit pAb

This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t (12;22) (p11. 2;q13. 3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],

Product Specifications

Background

This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t (12;22) (p11.2; q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Product Name Alternative

RASSF8; C12orf2; Ras association domain-containing protein 8; Carcinoma-associated protein HOJ-1

UniProt

Q8NHQ8

Swiss Prot

Q8NHQ8

Reactivity

Human; Rat

Immunogen

Synthesized peptide derived from RASSF8 . at AA range: 60-140

Target

RASSF8

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

48kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

48kD

Fragment

IgG

Other Product Names

RASSF8; C12orf2; Ras association domain-containing protein 8; Carcinoma-associated protein HOJ-1

Gene ID (Human)

11228

Available Sizes

Curated Selection

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