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IL-31Rα rabbit pAb

The protein encoded by this gene belongs to the type I Cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011],

Product Specifications

Background

The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR) . Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

Synonyms

IL31RA; CRL3; GPL; Interleukin-31 receptor subunit alpha; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; Cytokine receptor-like 3; GLM-R; hGLM-R; Gp130-like monocyte receptor; Gp130-like receptor; ZcytoR17

Gene ID

133396

UniProt

Q8NI17

Cellular Locus

Cell membrane ; Single-pass type I membrane protein. Cell junction, synapse, presynaptic cell membrane. Cell projection, axon.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from the Internal region of human IL-31Rα.

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

82kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3821-1.pdf

Observed Molecular Weight

82 kD

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, presynaptic cell membrane . Cell projection, axon .

Other Product Names

IL31RA; CRL3; GPL; Interleukin-31 receptor subunit alpha; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; Cytokine receptor-like 3; GLM-R; hGLM-R; Gp130-like monocyte receptor; Gp130-like receptor; ZcytoR17

Gene ID (Human)

133396

SwissProt (Human)

Q8NI17

Available Sizes

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