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MPP10 rabbit pAb

This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing. [provided by RefSeq, Dec 2010],

Product Specifications

Background

This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing. [provided by RefSeq, Dec 2010]

Synonyms

MPHOSPH10; MPP10; U3 small nucleolar ribonucleoprotein protein MPP10; M phase phosphoprotein 10

Gene ID

10199

UniProt

O00566

Cellular Locus

Nucleus, nucleolus. Chromosome. Fibrillar region of the nucleolus (PubMed:9450966). After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase (PubMed:9450966). In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin (PubMed:9450966). The reassociation with nucleolus is preceeded by the arrival of fibrillarin (PubMed:9450966)..

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from MPP10 . at AA range: 60-140

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA, IHC

Validated Applications

WB,ELISA,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Molecular Weight

78kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3809-1.pdf

Observed Molecular Weight

78 kD

Subcellular Location

Nucleus, nucleolus . Chromosome . Fibrillar region of the nucleolus (PubMed:9450966) . After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase (PubMed:9450966) . In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin (PubMed:9450966) . The reassociation with nucleolus is preceeded by the arrival of fibrillarin (PubMed:9450966) . .

Other Product Names

MPHOSPH10; MPP10; U3 small nucleolar ribonucleoprotein protein MPP10; M phase phosphoprotein 10

Gene ID (Human)

10199

SwissProt (Human)

O00566

Available Sizes

Curated Selection

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