MPP10 rabbit pAb

This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing. [provided by RefSeq, Dec 2010],

Product Specifications

Background

Product Name Alternative

MPHOSPH10; MPP10; U3 small nucleolar ribonucleoprotein protein MPP10; M phase phosphoprotein 10

UniProt

O00566

Swiss Prot

O00566

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from MPP10 . at AA range: 60-140

Target

MPP10

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Buffer

-20°C/1 year

Molecular Weight

78kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

78kD

Fragment

IgG

Subcellular Location

Nucleus, nucleolus . Chromosome . Fibrillar region of the nucleolus (PubMed:9450966) . After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase (PubMed:9450966) . In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin (PubMed:9450966) . The reassociation with nucleolus is preceeded by the arrival of fibrillarin (PubMed:9450966) . .