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Nup88 rabbit pAb

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

Product Specifications

Background

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Product Name Alternative

NUP88; Nuclear pore complex protein Nup88; 88 kDa nucleoporin; Nucleoporin Nup88

UniProt

Q99567

Swiss Prot

Q99567

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from Nup88 . at AA range: 330-410

Target

Nup88

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

83kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

83kD

Fragment

IgG

Subcellular Location

Nucleus, nuclear pore complex .

Other Product Names

NUP88; Nuclear pore complex protein Nup88; 88 kDa nucleoporin; Nucleoporin Nup88

Gene ID (Human)

4927

Available Sizes

Curated Selection

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