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SNM1B rabbit pAb

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al. 2000 [PubMed 10848582]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]) .[supplied by OMIM, Mar 2008]

UniProt

Q9H816

Swiss Prot

Q9H816

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human SNM1B.

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Molecular Weight

60kD

Storage Conditions

-20°C/1 year

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3794-1.pdf

Observed Molecular Weight

60kD

Fragment

IgG

Subcellular Location

Chromosome, telomere. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Mainly localizes to telomeres, recruited via its interaction with TERF2. During mitosis, localizes to the centrosome.

Other Product Names

DCLRE1B; SNM1B; 5' exonuclease Apollo; DNA cross-link repair 1B protein; SNM1 homolog B; SNMIB; hSNM1B

Gene ID (Human)

64858

Available Sizes

Curated Selection

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