APLP-1 rabbit pAb
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
APLP1; Amyloid-like protein 1; APLP; APLP-1
UniProt
P51693
Swiss Prot
P51693
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from APLP-1 . at AA range: 360-440
Target
APLP-1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
72kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
72kD
Fragment
IgG
Subcellular Location
Cell membrane; Single-pass type I membrane protein.; [C30]: Cytoplasm. C-terminally processed in the Golgi complex.
Other Product Names
APLP1; Amyloid-like protein 1; APLP; APLP-1
Gene ID (Human)
333
Available Sizes
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