MCAD rabbit pAb
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
ACADM; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD
Gene ID
34
UniProt
P11310
Cellular Locus
Mitochondrion matrix.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MCAD. AA range:134-183
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC
Validated Applications
WB,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
46kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3754-1.pdf
Observed Molecular Weight
46 kD
Subcellular Location
Mitochondrion matrix .
Other Product Names
ACADM; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD
Gene ID (Human)
34
SwissProt (Human)
P11310
Available Sizes
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