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ZFYVE19 rabbit pAb

Disease: A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t (11;15) (q23;q14) with MLL/HRX. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 FYVE-type zinc finger. tissue specificity: Detected in brain, heart, skeletal muscle, kidney and liver.

Product Specifications

Background

Disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML) . Translocation t (11;15) (q23; q14) with MLL/HRX., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 FYVE-type zinc finger., tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver.

Synonyms

ZFYVE19; MPFYVE; Zinc finger FYVE domain-containing protein 19; MLL partner containing FYVE domain

Gene ID

84936

UniProt

Q96K21

Cellular Locus

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody, Midbody ring. Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis..

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human ZFYVE19. AA range:311-360

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

50kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3729-1.pdf

Observed Molecular Weight

50 kD

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cleavage furrow . Midbody, Midbody ring . Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis. .

Other Product Names

ZFYVE19; MPFYVE; Zinc finger FYVE domain-containing protein 19; MLL partner containing FYVE domain

Gene ID (Human)

84936

SwissProt (Human)

Q96K21

Available Sizes

Curated Selection

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