XPA rabbit pAb
This gene encodes a Zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009],
Product Specifications
Background
Synonyms
XPA; XPAC; DNA repair protein complementing XP-A cells; Xeroderma pigmentosum group A-complementing protein
Gene ID
7507
UniProt
P23025
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human XPA. AA range:211-260
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
40kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3710-1.pdf
Observed Molecular Weight
40 kD
Subcellular Location
Nucleus .
Other Product Names
XPA; XPAC; DNA repair protein complementing XP-A cells; Xeroderma pigmentosum group A-complementing protein
Gene ID (Human)
7507
SwissProt (Human)
P23025
Available Sizes
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