Vimentin rabbit pAb
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract. [provided by RefSeq, Jun 2009],
Product Specifications
Background
Synonyms
VIM; Vimentin
Gene ID
7431
UniProt
P08670
Cellular Locus
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix. Cell membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Vimentin. AA range:56-105
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Molecular Weight
50-57kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3698-1.pdf
Observed Molecular Weight
50 - 57 kD
Subcellular Location
Cytoplasm . Cytoplasm, cytoskeleton . Nucleus matrix . Cell membrane .
Other Product Names
VIM; Vimentin
Gene ID (Human)
7431
SwissProt (Human)
P08670
Available Sizes
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