VEGF-B rabbit pAb
This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011],
Product Specifications
Background
Synonyms
VEGFB; VRF; Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF
Gene ID
7423
UniProt
P49765
Cellular Locus
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human VEGFB. AA range:91-140
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Molecular Weight
21kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3693-1.pdf
Observed Molecular Weight
21 kD
Subcellular Location
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Other Product Names
VEGFB; VRF; Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF
Gene ID (Human)
7423
SwissProt (Human)
P49765
Available Sizes
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