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VEGF-B rabbit pAb

This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011],

Product Specifications

Background

This gene encodes a member of the PDGF (platelet-derived growth factor) /VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1) . Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011]

UniProt

P49765

Swiss Prot

P49765

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human VEGFB. AA range:91-140

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.

Molecular Weight

21kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

21kD

Fragment

IgG

Subcellular Location

Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.

Other Product Names

VEGFB; VRF; Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF

Gene ID (Human)

7423

Available Sizes

Frequently Asked Questions

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