VEGF-B rabbit pAb
This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011],
Product Specifications
Background
UniProt
P49765
Swiss Prot
P49765
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human VEGFB. AA range:91-140
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Molecular Weight
21kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
21kD
Fragment
IgG
Subcellular Location
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Other Product Names
VEGFB; VRF; Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF
Gene ID (Human)
7423
Available Sizes
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