Tyk 2 rabbit pAb
Tyrosine kinase 2 (TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II Cytokine receptors and promulgate Cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
TYK2; Non-receptor tyrosine-protein kinase TYK2
Gene ID
7297
UniProt
P29597
Cellular Locus
Nucleus,cytoplasm,cytosol,cytoskeleton,membrane,extrinsic component of cytoplasmic side of plasma membrane,extracellular exosome,
Host
Rabbit
Species Reactivity
Human,Mouse,Monkey
Reactivity
Human; Mouse; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human TYK2. AA range:1020-1069
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Molecular Weight
134kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3658-1.pdf
Observed Molecular Weight
134 kD
Subcellular Location
Nucleus, cytoplasm, cytosol, cytoskeleton, membrane, extrinsic component of cytoplasmic side of plasma membrane, extracellular exosome
Other Product Names
TYK2; Non-receptor tyrosine-protein kinase TYK2
Gene ID (Human)
7297
SwissProt (Human)
P29597
Available Sizes
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