TRP2 rabbit pAb

Catalytic activity: L-dopachrome = 5, 6-dihydroxyindole-2-carboxylate. Cofactor: Binds 2 zinc ions per subunit. function: Involved in regulating eumelanin and phaeomelanin levels. pathway: Pigment biosynthesis; melanin biosynthesis. similarity: Belongs to the tyrosinase family. subunit: Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.

Product Specifications

Background

Catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate., cofactor:Binds 2 zinc ions per subunit., function:Involved in regulating eumelanin and phaeomelanin levels., pathway:Pigment biosynthesis; melanin biosynthesis., similarity:Belongs to the tyrosinase family., subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.

UniProt

P40126

Swiss Prot

P40126

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human DCT. AA range:51-100

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

60kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

60kD

Fragment

IgG

Subcellular Location

Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. .