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Tollip rabbit pAb

This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016],

Product Specifications

Background

This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

UniProt

Q9H0E2

Swiss Prot

Q9H0E2

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Tollip.

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

30kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

30kD

Fragment

IgG

Subcellular Location

Cytoplasm .

Other Product Names

TOLLIP; Toll-interacting protein

Gene ID (Human)

54472

Available Sizes

Curated Selection

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