TLE4 rabbit pAb
Caution: Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed: 15302935) would require further confirmation. function: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. similarity: Belongs to the WD repeat Groucho/TLE family. similarity: Contains 7 WD repeats. subunit: Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2. tissue specificity: In all tissues examined, mostly in brain, and muscle.
Product Specifications
Background
Synonyms
TLE4; KIAA1261; Transducin-like enhancer protein 4
Gene ID
7091
UniProt
Q04727
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human TLE4. AA range:161-210
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
83kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3615-1.pdf
Observed Molecular Weight
83 kD
Subcellular Location
Nucleus.
Other Product Names
TLE4; KIAA1261; Transducin-like enhancer protein 4
Gene ID (Human)
7091
SwissProt (Human)
Q04727
Available Sizes
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