TIMP-1 rabbit pAb
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
Gene ID
7076
UniProt
P01033
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat,Rabbit
Reactivity
Human; Mouse; Rat; Rabbit
Immunogen
The antiserum was produced against synthesized peptide derived from human TIMP1. AA range:61-110
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
IF, WB, IHC, ELISA
Validated Applications
IF,WB,IHC,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
24kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3609-1.pdf
Observed Molecular Weight
24 kD
Subcellular Location
Secreted .
Other Product Names
Gene ID (Human)
7076
SwissProt (Human)
P01033
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
