THC2 rabbit pAb

This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Feb 2010],

Product Specifications

Background

UniProt

Q96GX5

Swiss Prot

Q96GX5

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MASTL. AA range:821-870

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

97kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

97kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus . Cleavage furrow . During interphase is mainly nuclear, upon nuclear envelope breakdown localizes at the cytoplasm and during mitosis at the centrosomes. Upon mitotic exit moves to the cleavage furrow. .