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TH rabbit pAb

Tyrosine 3-monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have be associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Product Specifications

Background

Tyrosine 3-monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have be associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Synonyms

TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH

Host

Rabbit

Species Reactivity

Rat

Reactivity

Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Tyrosine Hydroxylase. AA range:5-54

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000.IHC-p:1:50-300 ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

58kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3602-1.pdf

Observed Molecular Weight

58 kD

Other Product Names

TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH

Available Sizes

Curated Selection

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