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TFIIE-β rabbit pAb

Function: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. similarity: Belongs to the TFIIE beta subunit family. similarity: Contains 1 TFIIE beta DNA-binding domain. subunit: Tetramer of two alpha and two beta chains. Interacts with FACT subunit SUPT16H.

Product Specifications

Background

Function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase., similarity:Belongs to the TFIIE beta subunit family., similarity:Contains 1 TFIIE beta DNA-binding domain., subunit:Tetramer of two alpha and two beta chains. Interacts with FACT subunit SUPT16H.

UniProt

P29084

Swiss Prot

P29084

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human TF2E2. AA range:151-200

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

33kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

33kD

Fragment

IgG

Subcellular Location

Nucleus .

Other Product Names

GTF2E2; TF2E2; Transcription initiation factor IIE subunit beta; TFIIE-beta; General transcription factor IIE subunit 2

Gene ID (Human)

2961

Available Sizes

Curated Selection

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