TAB182 rabbit pAb
PTM: ADP-ribosylated by TNKS1 (in vitro). PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. subcellular location: Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin. subunit: Binds to the ANK repeat domain of TNKS1 and TNKS2. tissue specificity: Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.
Product Specifications
Background
Synonyms
TNKS1BP1; KIAA1741; TAB182; 182 kDa tankyrase-1-binding protein
Gene ID
85456
UniProt
Q9C0C2
Cellular Locus
Nucleus. Cytoplasm, cytoskeleton. Chromosome. Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human TNKS1BP1. AA range:1601-1650
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
150kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3549-1.pdf
Observed Molecular Weight
150 kD
Subcellular Location
Nucleus. Cytoplasm, cytoskeleton. Chromosome. Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.
Other Product Names
TNKS1BP1; KIAA1741; TAB182; 182 kDa tankyrase-1-binding protein
Gene ID (Human)
85456
SwissProt (Human)
Q9C0C2
Available Sizes
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