SYT rabbit pAb
Disease: A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t (X;18) (p11. 2;q11. 2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency). similarity: Belongs to the SS18 family. tissue specificity: Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.
Product Specifications
Background
UniProt
Q15532
Swiss Prot
Q15532
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human SSXT. AA range:1-50
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
45kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
45kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
SS18; SSXT; SYT; Protein SSXT; Protein SYT; Synovial sarcoma translocated to X chromosome protein
Gene ID (Human)
6760
Available Sizes
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