What is the catalog number for SIRT1 rabbit pAb?

The catalog number for SIRT1 rabbit pAb is ES3447.

What sizes are available for SIRT1 rabbit pAb?

SIRT1 rabbit pAb is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does SIRT1 rabbit pAb come in?

SIRT1 rabbit pAb is available in 2 different pack sizes.

Is SIRT1 rabbit pAb in stock?

SIRT1 rabbit pAb is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SIRT1 rabbit pAb?

SIRT1 rabbit pAb is manufactured by ELK.

What is the estimated delivery time for SIRT1 rabbit pAb?

Estimated delivery time for SIRT1 rabbit pAb is approximately 10 business day(s), depending on your location.

SIRT1 rabbit pAb

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],

Product Specifications

Background

UniProt

Q96EB6

Swiss Prot

Q96EB6

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human SirT1. AA range:13-62

Clonality

Polyclonal

Source

Rabbit

Applications

IF; WB; IHC; ELISA

Concentration

1 mg/ml

Dilution

IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight

85-110kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

85-110kD

Fragment

IgG

Subcellular Location

Nucleus, PML body . Cytoplasm . Nucleus . Recruited to the nuclear bodies via its interaction with PML (PubMed:12006491) . Colocalized with APEX1 in the nucleus (PubMed:19934257) . May be found in nucleolus, nuclear euchromatin, heterochromatin and inner membrane (PubMed:15469825) . Shuttles between nucleus and cytoplasm (By similarity) . Colocalizes in the nucleus with XBP1 isoform 2 (PubMed:20955178) . .; [SirtT1 75 kDa fragment]: Cytoplasm . Mitochondrion .