Sarcoglycan-β rabbit pAb
This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy. [provided by RefSeq, Oct 2008],
Product Specifications
Background
Synonyms
SGCB; Beta-sarcoglycan; Beta-SG; 43 kDa dystrophin-associated glycoprotein; 43DAG; A3b
Gene ID
6443
UniProt
Q16585
Cellular Locus
Cell membrane, sarcolemma ; Single-pass type II membrane protein. Cytoplasm, cytoskeleton.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Sarcoglycan-beta. AA range:87-136
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
43kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3408-1.pdf
Observed Molecular Weight
43 kD
Subcellular Location
Cell membrane, sarcolemma ; Single-pass type II membrane protein . Cytoplasm, cytoskeleton .
Other Product Names
SGCB; Beta-sarcoglycan; Beta-SG; 43 kDa dystrophin-associated glycoprotein; 43DAG; A3b
Gene ID (Human)
6443
SwissProt (Human)
Q16585
Available Sizes
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