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Rho D rabbit pAb

Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

Product Specifications

Background

Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Synonyms

RHOD; ARHD; Rho-related GTP-binding protein RhoD; Rho-related protein HP1; RhoHP1

Gene ID

29984

UniProt

O00212

Cellular Locus

Cell membrane ; Lipid-anchor ; Cytoplasmic side. Early endosome. Colocalizes with RAB5 to early endosomes (By similarity)..

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human RHOD. AA range:113-162

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA, IHC

Validated Applications

WB,ELISA,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Molecular Weight

25kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3350-1.pdf

Observed Molecular Weight

25 kD

Subcellular Location

Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome . Colocalizes with RAB5 to early endosomes (By similarity) . .

Other Product Names

RHOD; ARHD; Rho-related GTP-binding protein RhoD; Rho-related protein HP1; RhoHP1

Gene ID (Human)

29984

SwissProt (Human)

O00212

Available Sizes

Curated Selection

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