What is the catalog number for Rag A/B rabbit pAb?

The catalog number for Rag A/B rabbit pAb is ES3318.

What sizes are available for Rag A/B rabbit pAb?

Rag A/B rabbit pAb is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Rag A/B rabbit pAb come in?

Rag A/B rabbit pAb is available in 2 different pack sizes.

Is Rag A/B rabbit pAb in stock?

Rag A/B rabbit pAb is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Rag A/B rabbit pAb?

Rag A/B rabbit pAb is manufactured by ELK.

What is the estimated delivery time for Rag A/B rabbit pAb?

Estimated delivery time for Rag A/B rabbit pAb is approximately 10 business day(s), depending on your location.

Rag A/B rabbit pAb

Function: Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14. 7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. similarity: Belongs to the GTR/RAG GTP-binding protein family. subcellular location: Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state. Colocalizes in vivo with adenovirus E3-14. 7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane. subunit: Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8. Interacts with adenovirus E3 14. 7 kDa protein. tissue specificity: Ubiquitously expressed with highest levels of expression in skeletal muscle, heart, and brain.

Product Specifications

Background

Function:Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity., similarity:Belongs to the GTR/RAG GTP-binding protein family., subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state. Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane., subunit:Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8. Interacts with adenovirus E3 14.7 kDa protein., tissue specificity:Ubiquitously expressed with highest levels of expression in skeletal muscle, heart, and brain.

UniProt

Q7L523/Q5VZM2

Swiss Prot

Q7L523/Q5VZM2

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human RRAGA/B. AA range:264-313

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

34kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

34kD

Fragment

IgG

Subcellular Location

Cytoplasm . Nucleus . Lysosome . Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state (PubMed:8995684, PubMed:9394008) . Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane (PubMed:8995684) . .

Other Product Names

RRAGA; Ras-related GTP-binding protein A; Rag A; RagA; Adenovirus E3 14.7 kDa-interacting protein 1; FIP-1; RRAGB; Ras-related GTP-binding protein B; Rag B; RagB