What is the catalog number for Rad51C rabbit pAb?

The catalog number for Rad51C rabbit pAb is ES3308.

What sizes are available for Rad51C rabbit pAb?

Rad51C rabbit pAb is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Rad51C rabbit pAb come in?

Rad51C rabbit pAb is available in 2 different pack sizes.

Is Rad51C rabbit pAb in stock?

Rad51C rabbit pAb is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Rad51C rabbit pAb?

Rad51C rabbit pAb is manufactured by ELK.

What is the estimated delivery time for Rad51C rabbit pAb?

Estimated delivery time for Rad51C rabbit pAb is approximately 10 business day(s), depending on your location.

Rad51C rabbit pAb

RAD51 paralog C (RAD51C) Homo sapiens This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Product Specifications

Background

RAD51 paralog C (RAD51C) Homo sapiens This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

UniProt

O43502

Swiss Prot

O43502

Reactivity

Human; Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human RAD51C. AA range:161-210

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight

50kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

50kD

Fragment

IgG

Subcellular Location

Nucleus . Cytoplasm . Cytoplasm, perinuclear region . Mitochondrion . DNA damage induces an increase in nuclear levels. Accumulates in DNA damage induced nuclear foci or RAD51C foci which is formed during the S or G2 phase of cell cycle. Accumulation at DNA lesions requires the presence of NBN/NBS1, ATM and RPA.