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Rab 6C rabbit pAb

Function: Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the small GTPase superfamily. Rab family. subunit: Interacts with SCYL1BP1. Interacts with VSP52 and RABGAP1. Isoform 1 interacts with RAB6KIFL but not isoform 2. Isoforms 1 and 2 interact with BICD1 and BICD2. Interacts with TMF1. tissue specificity: Ubiquitous.

Product Specifications

Background

Function:Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER) . Has a low GTPase activity., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the small GTPase superfamily. Rab family., subunit:Interacts with SCYL1BP1. Interacts with VSP52 and RABGAP1. Isoform 1 interacts with RAB6KIFL but not isoform 2. Isoforms 1 and 2 interact with BICD1 and BICD2. Interacts with TMF1., tissue specificity:Ubiquitous.

Synonyms

RAB6C; WTH3; Ras-related protein Rab-6C; Rab6-like protein WTH3

Gene ID

84084

UniProt

Q9H0N0

Cellular Locus

Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human RAB6C. AA range:165-214

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC

Validated Applications

WB,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300

Molecular Weight

28kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3292-1.pdf

Observed Molecular Weight

28 kD

Subcellular Location

Nucleus . Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .

Other Product Names

RAB6C; WTH3; Ras-related protein Rab-6C; Rab6-like protein WTH3

Gene ID (Human)

84084

SwissProt (Human)

Q9H0N0

Available Sizes

Curated Selection

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