Rab 20 rabbit pAb

Function: Plays a role in apical endocytosis/recycling. similarity: Belongs to the small GTPase superfamily. Rab family. subcellular location: Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules. tissue specificity: Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).

Product Specifications

Background

Function:Plays a role in apical endocytosis/recycling., similarity:Belongs to the small GTPase superfamily. Rab family., subcellular location:Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules., tissue specificity:Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level) .

UniProt

Q9NX57

Swiss Prot

Q9NX57

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human RAB20. AA range:115-164

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

28kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

28kD

Fragment

IgG

Subcellular Location

Golgi apparatus . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity) . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211) . .