PSCA rabbit pAb
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
Product Specifications
Background
Synonyms
PSCA; Prostate stem cell antigen
Gene ID
8000
UniProt
O43653
Cellular Locus
Cell membrane ; Lipid-anchor, GPI-anchor.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Prostate Stem Cell Antigen. AA range:41-90
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA, IHC
Validated Applications
WB,ELISA,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Molecular Weight
29kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3268-1.pdf
Observed Molecular Weight
29 kD
Subcellular Location
Cell membrane ; Lipid-anchor, GPI-anchor .
Other Product Names
PSCA; Prostate stem cell antigen
Gene ID (Human)
8000
SwissProt (Human)
O43653
Available Sizes
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