PSCA rabbit pAb
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
Product Specifications
Background
UniProt
O43653
Swiss Prot
O43653
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Prostate Stem Cell Antigen. AA range:41-90
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Molecular Weight
29kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
29kD
Fragment
IgG
Subcellular Location
Cell membrane ; Lipid-anchor, GPI-anchor .
Other Product Names
PSCA; Prostate stem cell antigen
Gene ID (Human)
8000
Available Sizes
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