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PSCA rabbit pAb

This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],

Product Specifications

Background

This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

UniProt

O43653

Swiss Prot

O43653

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human Prostate Stem Cell Antigen. AA range:41-90

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Molecular Weight

29kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

29kD

Fragment

IgG

Subcellular Location

Cell membrane ; Lipid-anchor, GPI-anchor .

Other Product Names

PSCA; Prostate stem cell antigen

Gene ID (Human)

8000

Available Sizes

Curated Selection

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