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PMEPA1 rabbit pAb

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

Product Specifications

Background

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM) . Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Product Name Alternative

PMEPA1; STAG1; TMEPAI; Transmembrane prostate androgen-induced protein; Solid tumor-associated 1 protein

UniProt

Q969W9

Swiss Prot

Q969W9

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human TMEPA. AA range:101-150

Target

PMEPA1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

37kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

37kD

Fragment

IgG

Subcellular Location

Early endosome membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.

Other Product Names

PMEPA1; STAG1; TMEPAI; Transmembrane prostate androgen-induced protein; Solid tumor-associated 1 protein

Gene ID (Human)

56937

Available Sizes

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