Plakophilin 2 rabbit pAb
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
PKP2; Plakophilin-2
Gene ID
5318
UniProt
Q99959
Cellular Locus
Nucleus. Cell junction, desmosome. Nuclear and associated with desmosomes.
Host
Rabbit
Species Reactivity
Human,Rat
Reactivity
Human; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PKP2. AA range:632-681
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA, IHC
Validated Applications
WB,ELISA,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Molecular Weight
97kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3232-1.pdf
Observed Molecular Weight
97 kD
Subcellular Location
Nucleus . Cell junction, desmosome . Nuclear and associated with desmosomes.
Other Product Names
PKP2; Plakophilin-2
Gene ID (Human)
5318
SwissProt (Human)
Q99959
Available Sizes
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