PDE4B/C/D rabbit pAb
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
Product Specifications
Background
Synonyms
Gene ID
5144/5142/5143
UniProt
Q07343/Q08493/Q08499
Cellular Locus
[Isoform PDE4B5]: Cytoplasm. Cell membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PDE4D. AA range:156-205
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
76kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3162-1.pdf
Observed Molecular Weight
76 kD
Subcellular Location
[Isoform PDE4B5]: Cytoplasm . Cell membrane .
Other Product Names
Gene ID (Human)
5144/5142/5143
SwissProt (Human)
Q07343/Q08493/Q08499
Available Sizes
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