NY-CO-9 rabbit pAb
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9
UniProt
Q9UQL6
Swiss Prot
Q9UQL6
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human HDAC5. AA range:1073-1122
Target
HDAC5
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Buffer
-20°C/1 year
Molecular Weight
121kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
121kD
Fragment
IgG
Subcellular Location
Other Product Names
HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9
Gene ID (Human)
10014
Available Sizes
Frequently Asked Questions
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