NKp46 rabbit pAb

Function: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. PTM: N-glycosylated. PTM: O-glycosylated. similarity: Belongs to the natural cytotoxicity receptor (NCR) family. similarity: Contains 2 Ig-like (immunoglobulin-like) domains. subunit: Interacts with CD3Z and FCER1G. tissue specificity: Selectively expressed by both resting and activated NK cells.

Product Specifications

Background

Function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis., PTM:N-glycosylated., PTM:O-glycosylated., similarity:Belongs to the natural cytotoxicity receptor (NCR) family., similarity:Contains 2 Ig-like (immunoglobulin-like) domains., subunit:Interacts with CD3Z and FCER1G., tissue specificity:Selectively expressed by both resting and activated NK cells.

Product Name Alternative

NCR1; LY94; Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NK-p46; NKp46; hNKp46; CD antigen CD335

UniProt

O76036

Swiss Prot

O76036

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human NCR1. AA range:145-194

Target

NKp46

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

40kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

40kD

Fragment

IgG

Subcellular Location

Cell membrane ; Single-pass type I membrane protein .

Other Product Names

NCR1; LY94; Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NK-p46; NKp46; hNKp46; CD antigen CD335