MYH14 rabbit pAb

This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],

Product Specifications

Background

This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14) . Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

UniProt

Q7Z406

Swiss Prot

Q7Z406

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MYH14. AA range:1051-1100

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight

228kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

228kD

Fragment

IgG

Subcellular Location

Stress fiber, cytosol, brush border, membrane, myosin complex, myosin II complex, axon, growth cone, actomyosin, myelin sheath, extracellular exosome, myosin II filament