MTHFR rabbit pAb
The protein encoded by this gene catalyzes the conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency. [provided by RefSeq, Oct 2009],
Product Specifications
Background
Product Name Alternative
MTHFR; Methylenetetrahydrofolate reductase
UniProt
P42898
Swiss Prot
P42898
Reactivity
Human; Mouse; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human MTHFR. AA range:314-363
Target
MTHFR
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Molecular Weight
75kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
75kD
Fragment
IgG
Subcellular Location
Cytosol, synapse
Other Product Names
MTHFR; Methylenetetrahydrofolate reductase
Gene ID (Human)
4524
Available Sizes
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