MRP-L50 rabbit pAb
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
MRPL50; 39S ribosomal protein L50; mitochondrial; L50mt; MRP-L50
Gene ID
54534
UniProt
Q8N5N7
Cellular Locus
Mitochondrion.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MRPL50. AA range:109-158
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA, IHC
Validated Applications
WB,ELISA,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Molecular Weight
22kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2843-1.pdf
Observed Molecular Weight
22 kD
Subcellular Location
Mitochondrion .
Other Product Names
MRPL50; 39S ribosomal protein L50; mitochondrial; L50mt; MRP-L50
Gene ID (Human)
54534
SwissProt (Human)
Q8N5N7
Available Sizes
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