MRP3 rabbit pAb
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
UniProt
O15438
Swiss Prot
O15438
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human ABCC3. AA range:971-1020
Target
MRP3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
170kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
170kD
Fragment
IgG
Subcellular Location
Basolateral cell membrane ; Multi-pass membrane protein .
Other Product Names
Gene ID (Human)
8714
Available Sizes
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