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MMP-19 rabbit pAb

This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013],

Product Specifications

Background

This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]

UniProt

Q99542

Swiss Prot

Q99542

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MMP-19. AA range:11-60

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

57kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

57kD

Fragment

IgG

Subcellular Location

Secreted, extracellular space, extracellular matrix .

Other Product Names

MMP19; MMP18; RASI; Matrix metalloproteinase-19; MMP-19; Matrix metalloproteinase RASI; Matrix metalloproteinase-18; MMP-18

Gene ID (Human)

4327

Available Sizes

Curated Selection

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