MLK4 rabbit pAb
Catalytic activity: ATP + a protein = ADP + a phosphoprotein. Cofactor: Magnesium. enzyme regulation: Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation. function: Activates the JUN N-terminal pathway. PTM: Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. similarity: Contains 1 protein kinase domain. similarity: Contains 1 SH3 domain. subunit: Homodimer.
Product Specifications
Background
Synonyms
MLK4; KIAA1804; Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4
Gene ID
84451
UniProt
Q5TCX8
Cellular Locus
Intracellular,
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MAP3KL4. AA range:631-680
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA, IHC
Validated Applications
WB,ELISA,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Molecular Weight
110kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2799-1.pdf
Observed Molecular Weight
110 kD
Subcellular Location
Intracellular
Other Product Names
MLK4; KIAA1804; Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4
Gene ID (Human)
84451
SwissProt (Human)
Q5TCX8
Available Sizes
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