NVP-BHG712 isomer
NVP-BHG712 isomer, a regioisomer of NVP-BHG712, shows conserved non-bonded binding to EPHA2 and EPHB4[1].
Product Specifications
CAS Number
2245892-85-5
UNSPSC
12352005
Target
Ephrin Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nvp-bhg712-isomer.html
Purity
99.32
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=CC=C(C=C1NC2=NC(C3=CC=CN=C3)=NC4=NN(C)C=C42)C(NC5=CC=CC(C(F)(F)F)=C5)=O
Molecular Formula
C26H20F3N7O
Molecular Weight
503.48
References & Citations
[1]Tröster A, et al. NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family. ChemMedChem. 2018 Aug 20;13 (16) :1629-1633.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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